With the rapid development of social and economic development, people put forward higher requirements on clothing, food, housing, work and product production process, product quality, etc. Clean workshop clean Engineering selection is becoming more and more common. How to reasonably select clean workshops and prevent the occurrence of errors and omissions, environmental pollution and cross-environmental pollution is one of the keys of GMP. Obviously, in the clean workshop, human body is the main source of environmental pollution. Therefore, human is the key factor to determine the occurrence of particulate air pollutants in the clean workshop. Every member of the clean workshop should grasp the influence of personal living habits on the cleanliness of the clean workshop in many ways, and follow the appropriate behavior to reasonably prevent the occurrence of anthropogenic particulate air pollutants in the clean workshop environment.
Key words: dust-free workshop purification, purification workshop engineering, workshop purification engineering, workshop workshop workshop purification, purification workshop decoration
How to effectively prevent environmental pollution in clean workshops?
1. Reasonable layout of space area
Reasonable layout should first clarify the production process and prevent circuitous roundtrip. The plane space of the studio should be reasonable, which is beneficial to both practical operation and maintenance. No vacant area and space can be reserved. Reasonable space and area are also conducive to reasonable zoning and prevention of chaotic safety accidents.
It should be noted that the cleaner the workshop is not the bigger the better, the size of the area and space is related to the amount of ventilation, determines the size of central air conditioning energy consumption, and affects the investment of the project. But the space area of the clean workshop can not be too small, too small may not be conducive to the actual operation and maintenance. Therefore, the design of reasonable space area should take into account the actual operation of machinery and equipment, maintenance needs. The production area and storage area shall be suitable for the scale of production and operation, and shall be used for the placement of machinery, equipment and raw materials, which is conducive to actual operation and maintenance. Normally, the height of the clean workshop is controlled at 2.60 meters, which can be partially increased for individual higher machinery and equipment, but is not suitable for further improving the height of the purification zone. There should be a positive intermediate station for raw materials in the production workshop, which has enough area to store raw materials, positive intermediate products, products to be tested and finished products, and is conducive to definite zoning, so as to reduce errors and leakage and cross-environmental pollution to a greater extent.
How to effectively prevent environmental pollution in clean workshops?
II. Raising the Level of Machinery and Equipment
The material of machine and equipment, the precision of production and processing, the degree of sealing and its management plan are all related to cross-environmental pollution. Therefore, in addition to reasonable layout, it is necessary to improve the automation technology level of machinery and equipment and form a linkage production line to reduce the actual operator and the activity frequency of personnel, so as to prevent cross-environmental pollution.
Dust production in solid preparation workshop is large. How to prevent cross-environmental pollution in solid preparation workshop? First of all, the selected machinery and equipment should have protective cover and ash removal device. Secondly, isolation measures should be selected and divided into operation room and front room or operation room and auxiliary room. In the layout of the front room, single machine and single room are usually used. The auxiliary room can be located in the non-purification area, and the maintenance door is located on the side of the corridor. Such separating methods can be used for machine equipment such as sheeting, automatic coating, rubber packing and so on. For some single machines without ash removal auxiliary machine and without sealing, such as crusher, powder or particle packer, the exhaust air in the isolation area can be filtered and sent back to the isolation area, which forms self-circulation.
How to effectively prevent environmental pollution in clean workshops?
3. Strictly Control the Flow of Personnel and Logistics
Clean workshops should have dedicated flow and logistics channels. Personnel should enter in accordance with the prescribed purification procedures, and the number of people should be strictly controlled. For raw materials, after dust removal, the outsourcing can be discarded and fed into the buffer room or transfer cabinet. Articles in the purification zone of different purification levels are transmitted according to the transfer window. The main and middle stations should be located in the central position, so as to shorten the transportation distance. There are no pipelines unrelated to the post in the purification area. Make full use of the upper and lower technical interlayer or the surrounding technical interlayer, all the main pipes of public pipelines and process pipelines are installed in the technical interlayer. Pipelines crossing the ground and partition walls should be as close as possible to the selected points and lay casing. Pipelines in the casing should not be welded, and sealing measures should be forked between the pipeline and the casing. The pipes entering the clean workshop shall be stainless steel type.
How to effectively prevent environmental pollution in clean workshops?
4. Separate air conditioning and purification systems
The air conditioning and purification system of clean workshop should be divided according to different cleanroom grades. For the studios of beta-lactams, contraceptives, hormones, virulent microorganisms, anticancer drugs and radiopharmaceuticals, air conditioning and purification systems should be set up, and high-efficiency filters should be installed in the vents to minimize the environmental pollution caused by such drugs. For clean workshops with different cleanroom grades, where dust and harmful gases occur, and where gases containing inflammable and explosive substances are discharged with high toxicity of medium, part of the ventilation system shall be set up separately. The air outlet of a clean workshop shall be an anti-backfilling device. The opening and closing of ventilation, ventilation and exhaust should be interlocked.
How to effectively prevent environmental pollution in clean workshops?
In a clean workshop, human beings are the key factors determining the occurrence of particulate air pollutants. The most important thing is to know how much the personal habits affect the cleanliness of the cleanroom. As for jewelry, workers can wear wedding and engagement rings, but try not to wear rings with sharp corners or edges, because they may stab their hands.