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1 Introduction
 Cosmetics GMP is based on "good manufacturing practices of cosmetic products ---- customer health protection" (referred GMPC) as a standard, based on a customer's health protection for third-party certification starting point. For the US and the EU market of cosmetics, both in domestic production or imported from abroad, the United States must comply with federal regulations or EU Cosmetics Cosmetics Directive, namely the implementation of GMP certification and comply with the relevant product standards (EN76 / 768 / EEC Directive), in order to ensure the health of consumers properly after use.
 
2 origin
Cosmetics GMPC certification, originated in the United States and Europe. In the United States, in 1962 had to cosmetic GMP legislation expressly provides that "drugs, cosmetics should be safe and effective according to law and with appropriate identification (including content labeling and instructions for use, side effects, precautions and other right shall not be adulterated)", later and specifically prohibit counterfeit or unbranded cosmetic promotion by the US Food and Drug Administration (FDA) in the trade between the United States each continent or pyramid schemes and developed a "Guide to cosmetic manufacturing activities" (ie GMPC, from FDA inspection manual part excerpt of the current 1992 version of the standard). European Commission in the early 1990s, also for cosmetic formulated the "Good Manufacturing Practice cosmetic products ---- health protection of customers" (referred GMPC, the current standard for the 1995 edition) and, subsequently, on the basis of the original done some Improvement, which aims to ensure the safe use of consumers as a starting point, intended to promote the conservation and understanding between Member States and the use of standards and guidelines for perfection, between the EC Member States to promote economic, trade to achieve a more harmonious, so that their economic and social progress, happy life for the people. In our country (China) does not yet have such strict requirements, but the trend is bound to cosmetic GMP, since the implementation of GMP enables enterprises to provide stable and reliable quality products with a solid guarantee; before, our country has set up "State Food and Drug Administration" has already established local levels corresponding provincial and municipal Food and Drug Administration, the safety of cosmetics are also placed under the supervision and daily management of the council of the unified management of cosmetics; According to information, the relevant departments After completion of drugs, health food GMP certification, we are ready to proceed to develop cosmetic GMP standards to respond after joining WTO, to strengthen our export of cosmetics (including "OEM, ODM" cosmetic) regulatory functions in place to protect the safety of consumers and health.
 3 Advantages
Target GMP management system is to eliminate and prevent quality defects in the manufacturing process, to avoid potentially dangerous cosmetic products for the user; GMP certification biggest advantage is: proven manufacturer of plant, personnel, facilities, procurement and use of materials and product manufacturing process control, factory and personnel health management, quality management systems have reached the world advanced level, have the ability to provide customers with safe and reliable product assurance, so that customers ease of use of its products.
 
Cosmetics manufacturers the choice of the site must comply with municipal Master Plan
1: cosmetics manufacturers should clean the area was built, and its production of toxic and hazardous pollution car distance less than 30 meters.
2: The cosmetics company shall not affect the surrounding residents living and safety, harmful substances or have severe noise production workshops and residential should have adequate health protection distance and protective measures.
3: cosmetics manufacturers factory planning should meet the health requirements, production areas, should be able to set up a non-production area to ensure continuity of production and must not have cross-contamination, it should be placed in clean production workshop area and located the local dominant upwind side.
4: Workshop production process and layout must meet health requirements. Cosmetics manufacturer principles should be set up between the raw materials, production room, among semi-finished products storage, filling, the packaging, container cleaning, disinfecting, drying, storage rooms, warehouses, laboratory, locker room, buffer zones, offices, etc., to prevent cross Pollution.
5: cosmetics production process generates dust or the use of hazardous, flammable, explosive materials in the product must use a separate workshop, specialized production equipment, and have the appropriate health and safety measures.
Waste water, waste gas, waste must be treated to meet the relevant national environmental, health requirements before discharge.
6: power, heating, air conditioning room, water supply and drainage system and waste water, waste gas, waste treatment systems and other auxiliary buildings and facilities should not affect the production plant health
 
Clean room technology requirements for cosmetics production
 
 According to the latest "maquiladoras health standards" clean plant design for the production of cosmetics have the following requirements demand.
 
1: cosmetics manufacturing plant can set the following premises: the locker room (according to need two layers), the buffer between the raw material pre-feed between the weighing room, studio, semi-finished products storage, filling room, packaging room, clean container. sterilization room, drying room, storage room, library materials, finished products, packaging materials, library, laboratory, sample room and so on.
2: The line between the rest of the production operations of the production, filling and packaging of the total area of not less than 100m2; simple packaging workshop between filling, packing room total area of not less than 80m2; each functional area laboratory, sample room, etc.) shall not be less than 10m2.
3: Production of cosmetics containing volatile organic solvents (such as perfume, nail polish, etc.) of the car and asked to be equipped with fire-related facilities.
4: Inter should pay particular attention to water problems making waterproof layer by coating the entire floor to ceiling lining. Other workshop waterproof layer shall not be less than 1.5m.
5: Workshop Face hybrid illumination of not less than 2001x, test place not less 200lx illuminance mixed Face To note here, mixing plus local lighting illumination means general lighting, it is impossible in post production are used local lighting.
6: As laboratory products production scale is small, small in size, the general tone is appropriate decentralized purification system according to cleanliness requirements with a different end of the filter efficiency.
Purification system:
1, clean clean room, central air conditioning and air purification system, but also purify the core of the system. Control the number of dust particles of air purification plant, regulate workshop temperature and humidity.
2, dressing room, air shower, clean room are the three basic components of the workshop purification system. Air shower is a passage out of the clean division, with the discharge of the high-speed clean air, effectively remove the body quickly brought the dust and bacteria. Clean room use color steel sandwich isolated space or wall, the upper color steel ceiling, floor paved with epoxy resin
Clean room decontamination
 
Purifying
Purify airflow early effect → → → in → purification efficiency of air-conditioning fan air duct → → → purification of air blown into the room → away bacteria and other dust particles blinds → → back to the early effect of air purification process is repeated, you can achieve the purpose of purification.
 
Purification parameters
ACH: 100,000 ≥15 times; 10000 ≥20 times; 1000≥30 times. Pressure: the main workshop adjacent room ≥5Pa
Average wind speed: 10, 100 0.3-0.5m / s; winter temperatures> 16 ℃; summer <26 ℃; fluctuation ± 2 ℃.
Temperature 45-65%; GMP powder workshop humidity around 50% is appropriate; electronic workshop slightly higher humidity to avoid static electricity.
Noise ≤65dB (A); fresh air replenishment is 10% -30% of the total air volume; illumination 300LX.
 
Sunshine Medical Equipment Co., Ltd Ed: to undertake: GMP biopharmaceutical clean room decontamination decoration, GPMC cosmetic decontamination decoration, QS food plant decontamination decoration, electronics factory decontamination decoration, all industries: ten ---- ---- three hundred thousand air purification engineering decoration and design.
Name: Sunshine charity Medical Equipment Engineering Co., Ltd.
Contact: Mr. Wang
Phone: 0633-6862777
E-mail: 2085888888@qq.com
Unified national service hotline: 400-0633-028
Official website: http: //www.kqjhgc.com