In experience, the number of clean air exchange in clean rooms with non-unidirectional flow is not the same. In the Code for the Design of Clean Workshops, the number of experienced air exchange required for the calculation of clean air supply in clean rooms with non-unidirectional flow at different levels is specified as follows: 50-60 times per 10000 level, 15-25 times per 100000 level, 10-15 times per 100000 level and 10-15 times per 100000 level and 10-15 times per million level. It should also be noted that the number of ventilation is suitable for clean rooms with a floor height less than 4.0m. The number of indoor people is small and the heat source is small. The lower limit value should be adopted. The number of ventilation in clean rooms with a floor height greater than 100,000 should not be less than 12 times. Animal laboratory ventilation should be more frequent, 8-10 times per hour in general environment, 10-20 times per hour in barrier environment and 20-50 times per hour in isolation environment.
Clean room temperature and relative humidity should be compatible with pharmaceutical production process. Without special requirements, the temperature should be controlled at 18 degrees 26 degrees, and the relative temperature should be controlled at 45% and 65%.
Clean room should maintain a certain amount of fresh air, and its value should take the maximum of the following air volume: 10% of the total air supply in non-unidirectional flow clean room, 2% and 4% of the total air supply in 30% unidirectional flow clean room; compensate for the amount of fresh air needed in the room and maintain the positive pressure value; ensure that the fresh air volume in the room per hour is not less than 40 m3.
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