Setting up is a systematic project, involving many factors such as long cycle, budget limitation, site limitation, geographical location, climate characteristics and so on. It needs systematic and closed-loop thinking and ideas. As the so-called knife sharpener and timber cutter, clean laboratory construction needs to lay a good foundation in the stage of laboratory design in advance, so as not to appear in the decoration stage, acceptance stage, use stage, or even later maintenance stage to find a variety of headache sequelae, I believe that many clean laboratory managers have had it. Similar failures.
So what factors should a good clean laboratory design pay attention to?
Firstly, the layout design of clean laboratory
The layout design of the clean laboratory is based on the nature of the clean laboratory, the target orientation of the clean laboratory, the functional requirements of the clean laboratory, the type of experiment and the process of experiment and other factors, and according to the relevant national standards, the scientific and reasonable functional distinction and layout of the existing sites of the clean laboratory are carried out.
The plane design of clean laboratory requires that the designer of clean laboratory must be familiar with the knowledge of building decoration, the relevant standards and norms of clean laboratory in China, and the experimental process of clean laboratory.
Second, Clean Laboratory Area and Instrument Placement
Before the design of the clean laboratory, the type, quantity, size, shape, voltage and power of the instrument and its placement should be determined according to the experimental process. The designer designs the power supply, water supply and drainage, air supply, purified water and the interface of the exhaust duct. According to the number and location of instruments, the required area of each area is determined, and the space for effective utilization is divided. The instrument placement should not only be convenient for work, but also consider the problem of ground load-bearing.
Third, ventilation system design
The ventilation system design of clean laboratory is the most important part in the design of clean laboratory, and it is also the key factor for the success or failure of the construction of clean laboratory. The ventilation system design of clean laboratory includes two aspects: exhaust system and supplementary air system.
The design of ventilation system in clean laboratory should be based on GB50019-2003 and GB50736-2012, respectively. The ventilation system in clean laboratory needs to pass the ventilation volume, length, direction and field practice required by actual clean laboratory. According to hydrodynamics, comprehensive analysis and calculation are carried out to design the ventilation system scientifically and reasonably, so as to achieve the goal of safety, comfort and energy saving in the design of clean laboratory.
Fourth, electrical engineering design
Electrical engineering design includes strong and weak electricity. In the aspect of strong electricity, it mainly includes instrument power consumption, lighting socket, etc. In the aspect of weak electricity, it includes network, data communication, broadcasting, video surveillance and so on.
Strong power design should be based on the sum of power of each instrument and equipment, according to the statistics of functional rooms, floors and the first level of the whole building, and the design of distribution system should be based on the relevant knowledge of electrical engineering. Each instrument room is separately equipped with a room terminal distribution box, and the main instrument needs a separate circuit, which can not be connected in series with room lighting or other sockets. This is mainly to meet the requirements of the use and maintenance of the instrument and equipment. Floor distribution boxes should be placed in special power distribution rooms with door locks, which need special management.
The clean laboratory should be equipped with UPS (Uninterruptible Power Supply) to provide protection for the main equipment of the clean laboratory. According to the electric parameters of clean laboratory equipment, the power and current parameters of uninterruptible power supply should be determined. It should be noted that the choice of uninterruptible power supply should reserve enough space for the development of clean laboratory. Considering the possibility of adding instruments and equipment to clean laboratory in the future and the parameters of planned purchasing instruments, the distribution negative should be fully reserved. Lotus.
Fifth, Water Supply and Drainage Design
The water supply and drainage of clean laboratory includes tap water and pure water. Because the best way of water supply and drainage of clean laboratory is to use hidden clothes, if there are omissions in the design, it will bring great inconvenience and trouble to the later management of clean laboratory.
Generally speaking, the water supply pipeline of clean laboratory adopts high quality U-PVC pipeline, the supervisor can choose 6', the branch pipe can choose 4'; the drainage pipe can choose high quality PPR pipeline, generally choose 50 or 75, and in special cases, 110.
Pure water, according to the amount and grade of pure water required for full-load operation of all equipment to determine the appropriate water-making equipment, water treatment capacity of selected equipment should also be reserved enough space.
6. Temperature and Humidity Requirements for Clean Laboratory (Air Conditioning System)
The temperature and humidity of the clean laboratory should be designed according to the requirements of the experiment. Ordinary physical and chemical rooms can be operated by ordinary split air conditioning or on-line. For precision instrument room, there are certain requirements for temperature and humidity, such as ICP, ICP-MS and so on. There are also some special requirements for temperature and humidity, such as fiber inspection, paper inspection, textile fabrics and so on. Designers in the design of such a clean laboratory are required to select materials according to standards.
The standard atmosphere for textile and textile raw materials inspection is stipulated by ISO139 and GB6529 standards, the temperature is 20 +1 C and the relative humidity is 65%+2%. The standard atmosphere for paper, paper and carton commodities inspection is stipulated by ISO187 and GB10739 standards, the temperature is 23 +1 C and the relative humidity is 50%+2%. In addition to the conventional constant temperature and humidity clean laboratories, there are other special constant temperature and humidity clean laboratories with special requirements such as 5-18 C low temperature, 30-80 C high temperature, low relative humidity less than 40% RH and high relative humidity higher than 80% RH.
Seventh, Illumination and Noise Control Design
According to the building technical specifications of BSL-2 clean laboratory, the illumination and noise of BSL-2 clean laboratory should not be less than 300 Lux and 68 dB6 respectively. Before the interior decoration of the clean laboratory, the illumination requirement of the clean laboratory was put forward to the construction party. After the completion of the test, the illumination of the machine room was 285-319 lux, and the illumination of the core working area was 375-384 lux, which basically met the BSL-2 standard for the construction of the clean laboratory. The environmental noise of the clean laboratory is obviously reduced after taking measures such as water and electricity independence, especially in the relatively independent core working area, the decibel number measured is basically the same as that in the general clinic.
Purification and Purification Level
Before construction, biosafety assessment should be carried out according to the general guidelines for biosafety of microbial and biomedical clean laboratories, the general requirements for biosafety of GB19489-2008 clean laboratories, and the regulations for biosafety management of pathogenic microorganisms clean laboratories (Decree 424 of the State Council), so as to determine whether clean laboratories need purification and purification. Grade 2-4.
In actual design, the indicators of clean laboratory fully meet the requirements of BSL-2 clean laboratory, including clear identification, independent changing room, independent warehouse, equipped with eye washer, high-pressure steam sterilizer and emergency tools. In addition, some requirements of BSL-3 clean laboratory construction are also referred to in the design. The height of the floor is not less than 2.6m, the net width of the passageway in the clean laboratory is not less than 1.5m and the width of the door is not less than 1m. At the same time, the height and width of the door should be convenient for the transportation of instruments in the clean laboratory. After completion, the access control system, ventilation frequency, temperature and humidity control of the clean laboratory have reached the level of BSL-3 clean laboratory.
To sum up, the construction of clean laboratory is a systematic project, which is different from the general design and construction of business or office environment. It requires professional team system operation and elaborate construction plan. Shandong Aide Purification Engineering Co., Ltd. is a professional manufacturer of laboratory planning and design, engaged in laboratory decoration, laboratory design, laboratory renovation and other business for many years. The company has a professional laboratory design team, covering the laboratory decoration and construction team. Clean Laboratory Construction Clean Laboratory Design Clean Laboratory Decoration Clean Laboratory Planning Seek Edward Purification. To learn more about the medical purification industry, please pay attention to the Wechat Public No. Aide-188 (Ed Purification and Oxygen Supply)