Clean room generally implemented two levels of isolation, a level of isolation through biological safety cabinets, negative pressure isolators, positive pressure protective clothing, gloves, goggles and so on; secondary isolation through the laboratory building, air conditioning and electrical control system to achieve purification. However, due to the small amount of clean air conditioning needs for safety reasons, the air volume are large estimates, generally exceed the norms, the object is more than one hundred, the heat load in the request is not very strict situation may be estimated, and now specialized purification air conditioning Unit, can be used directly. Two to four biosafety laboratories should implement two levels of isolation. General laboratory equipment: clean benches, biological safety cabinets, side or stainless steel console, washing Taiwan and so on.
PCR Laboratory Purification Project
Take PCR laboratory as an example (PCR is polymerase chain reaction), which is a routine method for molecular biology research and experiment. It is also a widely used experimental technique in the field of biology and medical clinic. It is characterized by a substantial increase in trace amounts of DNA. The laboratory is usually divided into four areas: reagent storage and preparation area, specimen preparation area, amplification reaction mixture preparation and amplification area, amplification product analysis area Automatic analyzer, the region may be appropriate to merge). Access to all areas must be strictly in accordance with a single direction, different work areas using different overalls (for example, different colors). Workers are not allowed to bring work clothes out.
Reagent storage and preparation room (specimen preparation area), the instrument is mainly equipped with: refrigerated centrifuge, bio-safety cabinets, refrigerators, removable UV lamp, automatic purification of nucleic acid protein, special work clothes and work shoes. Amplification reaction mixture preparation and amplification area equipped with: refrigerator, high-speed centrifuge, clean bench, PCR instrument (requires negative pressure), removable UV lamp, micro sampler, nucleic acid amplification instrument. Amplification product analysis area is mainly equipped with: pipette, oscillator, clean bench, capillary electrophoresis, refrigerator, centrifuge, micro sampler, removable UV lamp. PCR laboratory design as shown below:
PCR laboratory purification project overlooking the map
Top view of PCR lab
PCR Laboratory Purification Project Floor Plan
PCR laboratory plan
Electronic computer room and laboratory, computer and our life most closely, mainly consider the air conditioning cooling, power supply voltage and other issues. The equipment is mainly equipped with the keyboard and keyboard equipment Taiwan. The institute is mainly for the research staff office, less demanding on our laboratory equipment, not much to explain here.
Auxiliary laboratory: The main balance room, high temperature room, pure water room, cylinder room, storage room, solution preparation room, darkroom and so on. Balance room, analytical balance is a necessary laboratory equipment commonly used instruments, high-precision balance on the environment have certain requirements, mainly airflow and wind speed, balance room should be close to the chemical laboratory to facilitate the use, but not with the high temperature chamber and Rooms with strong electromagnetic interference are adjacent. High-precision micro balance should be set at the bottom. Do not set the balance inside the washing station or any pipe through the stifling, so as to avoid pipe leakage affect the balance of maintenance and use. High-temperature room, high temperature furnace and incubator are standing equipment, generally placed on the high temperature workbench, but large-scale incubator to be placed on the ground appropriate, the thermostat oven thermostat to be placed separately. Pure water room, mainly designed with experimental equipment; side and washing Taiwan. Modern laboratories to use more deionized water, water and ensure water quality. Floor to be provided floor drain. Gas cylinders, laboratory gases In addition to non-combustible gases (nitrogen, carbon dioxide), inert gases (argon, helium, etc.), other gases with high pressure, highly toxic, oxidative decomposition, explosion and other dangerous gases, Hydrogen, carbon monoxide; highly toxic gases for the fluorine, chlorine; combustion gas is oxygen, etc., these gases may not be laboratory. Can be received through the tube to the laboratory. Solution preparation chamber, used to prepare a variety of standard solutions and different concentrations of solution. Under the conditions allowed, it can be composed of two rooms, one with a sky platform. Another preparation reagents and storage reagents used, the general should be configured: fume hood, bench, reagent cabinet.
The service provision part, for the basic laboratory and auxiliary laboratory service place, such as the pressure cooker room and the hydropower auxiliary room and so on. We only need a little understanding.
Work procedures, professional design process
The first part is a graphic design, Party A (the user) first come up with the most basic functional requirements, distribution programs, Party B (Design Institute), Party C (Laboratory Planning and Design Professional) and Party A to participate in the laboratory construction design team , Discuss together, the three sides together to confirm the rear into the second procedure. Because the traditional laboratory building design by national building standards, only the appearance and interior structure-based, not primarily laboratory functions, architectural design and functional design out of touch. Our company has many lessons in this area. For example, Guangdong Medical College, signed a contract for two years because the site does not meet the installation conditions, has not been installed.
The second part is a single function, a single structure design, should be item by item, piece by piece, layer by layer, from the entire building, stratification, sub-room, sub-piece design to determine, fully subdivided to confirm;
The third part, after all confirmed, inviting users to participate in senior leadership laboratory building presentations, the spot position decision; please by Party B, Party C project supervision and strict supervision of the installation, the construction process standards tracking laboratory construction project The successful completion of the construction laboratory planning and design and product tendering is divided into two parts; tender: A, the design for the first part; B, product standards for the second part of the building decoration, cleaning, basic equipment in three professional, not mixed the total package, different professions, were tender, and then work closely with the tripartite bid, decoration and decontamination first, after the date of acceptance laboratory infrastructure facilities will enter the stage of accountability, responsibility, focus on three simultaneous acceptance, as part of the basic equipment when fully completed Product testing standards, testing and the first two projects are different, there is a big difference can not be treated equally.
Floors, walls, smooth ventilation, to prevent dead ends, indoor four corners as free, easy to care, simple.
Single structure function design system
Different professional use of different laboratory-based basic equipment, the product is divided into five parts: A, the test bench part; B, instrument Taiwan part; C, functional cabinets section; D, equipment and equipment; E, the output system part.
A, the experimental section
1, the classification of the test bed:
① laboratory bench according to the function of the laboratory is divided into: physical test bench (mainly for electronics, electrical, physical experiments); chemical test bench (mainly for organic and inorganic chemistry experiments); biological test bench Experiments, such as simple dissection Taiwan, stainless steel console, etc.);
② according to the structure zoned models are divided into: MM (composed of steel support frame, base box, countertops, reagent rack, connectors, accessories) MR (base box, countertops, reagent rack, connectors, accessories);
③ According to the use can be divided into: the central experimental bench, bench side bench, washing bench, reagent rack, base box, experimental stool.
2, the base of the classification:
Base box can be divided according to the material: steel wooden base box, aluminum wooden base box, all wooden base box.
According to the production process is divided into: European-style steel base box (that is, the connection of the door and the side panels), steel American base box (that is, the door panel embedded in the base box).
By style can be divided into: mobile base box, floor-based base box, hanging base box. Including mobile base box, hanging base box for MM models. Floor base for MR models. Steel wooden base box is our company newly developed products, side panels, door panels made of steel, the other such as laminates, roof, drawer bottom, repair board are made of wood, with fire safety, cost-effective, glassware Not easy to place when placed and so on. All wood is not suitable for making hanging baskets and wash basins.
B, instrument Taiwan part
Load-bearing, stability, anti-interference, high electrical control requirements, gas distribution strict, safe, reliable, convenient and easy to manage; Load: 500Kg above. Mainly used in instrumental analysis laboratories, such as spectroscopy, chromatography, atomic analysis laboratories. The major products are: standard instrument Taiwan, Taiwan spectrum instrument, chromatography instrument Taiwan, microscope Taiwan, Siamese instrument Taiwan, Tian platform, computer Taiwan, high-temperature equipment Taiwan, teaching Taiwan.
C, functional section of the cabinet
Functional cabinets are part of the first two parts of the service, storage, important features related to safety and environmental issues; all wood and steel wood points; reagents, pharmaceuticals, volatile drugs, radiopharmaceuticals, drastic drugs, flammable culture storage Function basically divided into thirteen kinds:
1, the general performance of medicine cabinets; 2, volatile drug storage cabinets; 3, dye cabinets; 4, radiation cabinet drugs; 5, combustible goods storage cabinets (fireproof cabinets) 7, more wardrobe (brake bacteria wardrobe); 8, training cabinets; 9, specimen cabinets; 10, instrument cabinets; 11, soda ash cabinets;
D, equipment part
1, fume hoods; 2, biological safety cabinets; 3, clean workbench; 4, utensils washing machine (fully automatic); 5, safe drug storage cabinet; 6, intelligent cabinet intensive; Taiwan; 9, sensing function cabinets; 10, volatile medicine cabinet.
E, harmful gas output part, will be described in detail in the following chapters, here do not repeat.
Water supply and drainage design system
Water supply and drainage design system is mainly for pre-laboratory building design services. For the architectural design institute to provide experimental platform water points. The faucet is divided into two parts, one is the water faucet and the other is the water faucet. The single faucet (MBs-016) is the faucet. General with PP sink (MBc-032). Double nozzle (MBs-02) for the slow flow nozzle, usually with PP tank (MBc-029) specifications. By default, we generally configure double tap for customers. Triple water faucet (MBc-01) for a quick two water mouth. General with PP sink (MBc-029). Large tank (MBc-031), fume hood cup (MBc-028).
Electronic control system
Laboratory electricity mainly includes lighting and power two major parts. Power is mainly used for various types of electrical equipment, elevators, air conditioners and other power supply. Laboratory power supply system is also one of the most basic laboratory conditions. Power outlets are: 10A, 13A, 16A, 20A; leakage protection switch, overload protection switch. Power outlet should be away from the basin and gas, hydrogen and other nozzle openings, does not affect the test bench apparatus placement and operation position. Trunking The main multi-purpose steel trunking (mainly used for reagent rack) and PVC trunking with the Spanish socket (mainly for the side and the central Taiwan table top).
Special gas distribution system
Laboratory gas is mainly non-flammable gases (nitrogen, carbon dioxide), inert gases (argon, helium, etc.), flammable gases (hydrogen, carbon monoxide); highly toxic gases (fluorine, chlorine) . In addition to non-flammable gases, inert gases other than the gas laboratory. Can be connected to the laboratory through the gas pipe. General gas phase chamber equipped with helium (He), nitrogen (N2). GC / MS is equipped with nitrogen, hydrogen and oxygen. Hydrogen pipeline connecting pipe fittings are connected after the welding is strictly prohibited the possibility of a leak. All pipelines must be tested airtight after installation and degrease before use. Due to the small pipe size and small pipe spacing, the installation process can be adjusted according to the site conditions to ensure that the spacing is not less than 45mm. When the cylinder is bottled, flammable and explosive should be inert gas with the same cabinet to prevent the two flammable gases from being installed in the same bottle.
Harmful gas output system
In the introduction of the ventilation system, we will list it separately for analysis.
点击图标下载 App